
Nicholas Flamel got the book of Abraham the Mage in which there was a secret recipe for the construction of an elixir with the help of which a man can live forever. For centuries according to the legend, Nicholas has been making that elixir to keep himself alive. The book which he has is quite beneficial but it can prove to be deadly too if it lands in the wrong hands.
Dr. John Dee is one of the men who want to misuse the book to gain control of the world. The Magician and The Warlock are other parts of this series that would become hard to understand if you leave this introductory part. Sophie and Josh are two characters who come a little later in the novel but one should not underestimate their importance. These two are the chosen ones according to prophesy and only they can save Flamel and the book from John Dee.